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They're especially important for severe deficiencies

In this work, we show that ROXY9 has weak GSH-dependent de-glutathionylation activity on glyceraldehyde-3-phosphate dehydrogenase (GAPDH), but no oxidase or reductase activities on other substrates like HED, Cys-SG, cumene hydroperoxide (CHP) or roGFP2

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Iron deficiency is a common nutrient deficiency