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These superoxide anions are then converted into hydrogen peroxide (H 2 O 2 ) by superoxide dismutase ( 2 - can interact with NO to produce reactive nitrogen species (RNS), such as the highly toxic peroxynitrite ( Figure 2A ) ( Figure 2B )

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Further studies are needed to investigate the exact mechanisms of action of vitamin E in AD and the involvement of GSTO1 inhibition in this process

However, 23 per week for 4 weeks, then weekly maintenance is a typical dose for longevity support