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The variation depends mainly on the material used for making paperboards as well as the composition of the natural tobacco blend within the cigarette, including moisture

Considering the consequences Otis Brawley, chief medical officer of the American Cancer Society, says the study is easy to believe. The smaller particles in filtered cigarettes get past the bronchial tubes into the smaller tubes, called bronchioles, he said, explaining that this irritates the tissue in the periphery of the lung, where adenocarcinomas are found

Reuters.com

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Fewer tobacco components, simpler processing, streamlined supply chains enable cost reduction offsetting the specialty manufacturing