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The study was funded, in part, by the National Heart, Lung, and Blood Institute of the National Institutes of Health (grant # R01HL103684), the National Institutes of Health (grant #T32HL079891-11, grant #T32 GM084896), the Tobacco-Related Disease Research Program (awards # T31KT1501, #T33PC6863, #T32PT6244, #T32PT6042 and #T32IR5208), the National Cancer Institute (#K01 CA234317), the San Diego State University/ UC San Diego Comprehensive Cancer Center Partnership (#U54 CA132384 and #U54 CA132379), and the Alzheimers Disease Resource Center for Advancing Minority Aging Research at UC San Diego (#P30 AG059299)
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It was demonstrated that human breast cells exposed to low-dose environmental endocrine-disrupting compounds, can up-regulate aromatase activity and importantly, increase the intracellular biosynthesis of 17-estradiol [54, 55]
